(2-CYANO-6-FLUOROPHENYL)BORONIC ACID PINACOL ESTER

(2-CYANO-6-FLUOROPHENYL)BORONIC ACID PINACOL ESTER - Names and Identifiers

Name	Benzonitrile, 3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
Synonyms	(2-CYANO-6-FLUOROPHENYL)BORONIC ACID PINACOL ESTER 3-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ben 3-Fluoro-2-(tetraMethyl-1,3,2-dioxaborolan-2-yl)benzonitrile Benzonitrile, 3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
CAS	624741-47-5

(2-CYANO-6-FLUOROPHENYL)BORONIC ACID PINACOL ESTER - Physico-chemical Properties

Molecular Formula	C13H15BFNO2
Molar Mass	247.07
Density	1.12±0.1 g/cm3(Predicted)
Boling Point	354.0±32.0 °C(Predicted)
Water Solubility	Slightly soluble in water.
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

(2-CYANO-6-FLUOROPHENYL)BORONIC ACID PINACOL ESTER - Introduction

Benzonitrile, 3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, with the chemical formula C14H16BFNO2, is also known as 3-fluoro-2-(4,4,5,5-tetramethyl-1,3, 2-dioxopentadienyl)-benzonitrile boronate. The following is a detailed description of its nature, use, formulation and safety information:

Nature:
-Appearance: colorless liquid
-Molecular weight: 273.09g/mol
-Melting point: No data
-Boiling Point: 109-111°C
-Density: 1.075g/cm3
-Solubility: Soluble in organic solvents (such as ether, alcohol, ketone, etc.)

Use:
- Benzonitrile, 3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-is a commonly used reagent in organic synthesis, which can be used to construct and modify the skeleton of organic molecules.
-it is often used as an active reagent in organic synthesis for catalytic and promoting acylation, aminolysis and other reactions.
-This compound can also be used as raw materials for pharmaceutical synthesis, rubber manufacturing, dye synthesis and other industrial fields.

Preparation Method:
- Benzonitrile, 3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-can be synthesized by the following steps: first, 4,4,5,5-tetramethyl-1,3, 2-dioxopentadiene (DMBD) and trifluorobenzene borate are reacted to obtain the intermediate product, and then esterified with fluorobenzonitrile to generate the target product.

Safety Information:
- Benzonitrile, 3-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-No special safety risks under normal use and storage conditions.
-However, as organic compounds, care should be taken to avoid inhalation, skin contact and swallowing.
-Wear appropriate personal protective equipment (e. g. goggles, gloves and overalls) when using.
-After the operation, clean the contaminated skin in time and pay attention to avoid release into the environment.
-Correct laboratory practices and safe practices should be followed when handling the compound.

Last Update：2024-04-09 20:45:29